R Packages

psborrow2

psborrow2 is an R package that for conducting Bayesian Dynamic Borrowing (BDB) analyses and simulation studies.psborrow2 has two main objectives:

  1. Facilitate BDB analyses. psborrow2 has a user-friendly interface for conducting BDB analyses that handles the computationally-difficult MCMC sampling on behalf of the user.

  2. Facilitate simulation studies of BDB. psborrow2 includes a framework to compare different trial and BDB characteristics in a unified way in simulation studies to inform trial design.

Install with:

remotes::install_github("Genentech/psborrow2")

More information on https://genentech.github.io/psborrow2/main/index.html.

rdborrow

rdborrow is an R package for causal inference incorporating external controls in randomized controlled trials with longitudinal outcomes. It provides tools to borrow information from external control data—useful in settings such as rare disease trials—to strengthen analysis and support simulation studies.

Install with:

remotes::install_github("Genentech/rdborrow")

More information on https://genentech.github.io/rdborrow/.

survivalCCW

This is a lightweight, work-in-progress package that prepares data for clone censor weight analyses in R.

Install with:

remotes::install_github("Genentech/survivalCCW")

More informaton on https://genentech.github.io/survivalCCW/.